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Journal of Mental Science (1958) 104: 1062-1068. doi: 10.1192/bjp.104.437.1062
© 1958 The Royal College of Psychiatrists
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Treatment of Anxiety States

III. Components of Anxiety and Their Response to Benactyzine

Max Hamilton, M.D., D.P.M., Senior Research Fellow

Leeds University Department of Psychiatry, The General Infirmary at Leeds

ABSTRACT

A controlled trial of the drug benactyzine was carried out on 26 patients suffering from Anxiety Neurosis, using a rating scale for 13 symptoms (variables). The relations between the variables show that they may be effectively replaced by three independent index numbers or factors. Replacing the thirteen measures for each patient by three factor measurements, the improvement occurring in each patient was then calculated. On comparing the mean improvement produced by benactyzine and that occurring in the controls, statistical tests show that this difference is highly significant in the case of the third factor. The implications of this are discussed.







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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1958 The Royal College of Psychiatrists.