Journal of Mental Science (1959) 105: 685-692. doi: 10.1192/bjp.105.440.685
© 1959 The Royal College of Psychiatrists
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*Indoluria in Schizophrenia:

II. Chromatographic Study on 40 Schizophrenic and 10 Normal Subjects

A. D. Forrest, M.R.C.P., D.P.M., Lecturer in Psychological Medicine

University of Edinburgh

* Based on work already submitted for the Degree of M.D. at the University of St. Andrews.

ABSTRACT

  1. Concentrates were made from urine samples collected from 25 male and 15 female schizophrenic subjects, 10 normal subjects were also studied.
  2. These concentrates were used in two-way ascending chromatograms and an attempt was made to identify the indoles detected.
  3. One "abnormal" spot ("Q.F.B.") was found in 23 schizophrenic subjects and in 7 out of the 10 catatonic patients (70 per cent. incidence).
  4. These results are discussed in relation to other reports on the excretion of indoles in schizophrenia.