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ABSTRACT
Summary and Conclusion: The case histories of four related patients are briefly described. All have been afflicted by atypical psychoses. The positive features common to all of them are a sudden onset with depression and marked feelings of unreality and loss of self-respect. The similarity in the illnesses of the identical twins is most striking.
The family provides an example of a heredo-familial disorder with atypical features and a relatively benign course. The response to leucotomy in one patient is noteworthy.
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