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The British Journal of Psychiatry (1963) 109: 411-417. doi: 10.1192/bjp.109.460.411
© 1963 The Royal College of Psychiatrists
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Chlorpromazine and Trifluoperazine in the Treatment of Behavioural Abnormalities in the Severely Subnormal Child

H. HUNTER M.B., B.S., D.P.M.1 and G. M. STEPHENSON B.A.2

1 Medical Superintendent, Balderton Hospital
2 Research Psychologist, Nottingham University

A controlled drug trial is reported comparing trifluoperazine and chlorpromazine. Results show that both of these drugs are significantly effective in the control of hyperactivity and behavioural abnormalities in severely subnormal children. Trifluoperazine showed a slight superiority over chlorpromazine, but the difference was not statistically significant.




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Copyright © 1963 The Royal College of Psychiatrists.