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The British Journal of Psychiatry (1963) 109: 422-427. doi: 10.1192/bjp.109.460.422
© 1963 The Royal College of Psychiatrists
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Withdrawal of Perphenazine in Chronic Schizophrenia

C. B. WHITTAKER M.B., Ch.B., D.P.M.1 and R. M. HOY M.A.2

1 Registrar, Bellsdyke Hospital, Larbert.(Assistant Psychiatrist, Gartloch Hospital, Glasgow.)
2 Principal Clinical Psychologist, Bellsdyke Hospital, Larbert

A controlled trial concerning abrupt withdrawal of perphenazine in chronic schizophrenic patients in hospital is reported. A special feature is the use of two types of control group, enabling the relative importance of pharmacological and placebo effects to be assessed. Advantages of this method are discussed, and implications regard-the feasibility of discontinuous perphenazine treatment are drawn.




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Copyright © 1963 The Royal College of Psychiatrists.