The British Journal of Psychiatry (1963) 109: 491-499. doi: 10.1192/bjp.109.461.491
© 1963 The Royal College of Psychiatrists
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A Follow Up Study of Schizophrenia and Depression in Young Adults

JOHN A. CLARK M.B., M.R.C.P.E., D.P.M.1 and BERNARD L. MALLETT M.B., M.R.C.P., D.P.M.2

1 Consultant Physician, Crichton Royal
2 Research Fellow, Guy's Hospital

A three-year follow-up study is described of 186 patients under the age of thirty, of whom 86 had been diagnosed schizophrenic, 82 depressive, and 18 schizo-affective disorder. Follow-up was complete for 90 per cent. of patients.

Approximately 70 per cent. of the schizophrenic group required admission to a mental hospital within the three-year period, and 93 per cent. of those admitted were again diagnosed schizophrenic. Of the depressive group, 20 per cent. required admission, of whom about two-thirds again had depressive illnesses and one-third were diagnosed schizophrenic.

There were three suicides, all from the original schizophrenic group.

The investigation, which was undertaken to test the validity of the diagnoses "schizophrenia" and "depression", shows that simple be havioural characteristics of the follow-up record are sharply different in the two cases. In these respects cases diagnosed as "schizo-affective" occupied an intermediate position.




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