BJP Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
QUICK SEARCH:   [advanced]


     

The British Journal of Psychiatry (1965) 111: 142-148. doi: 10.1192/bjp.111.471.142
© 1965 The Royal College of Psychiatrists
This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by SANDIFER, M. G.
Right arrow Articles by GAMBILL, J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SANDIFER, M. G., Jr.
Right arrow Articles by GAMBILL, J. M.

The Influence of Case Selection and Dosage in an Antidepressant Drug Trial

M. G. SANDIFER Jr. M.D., F.A.P.A.1, I. C. WILSON M.B., D.P.M.2, and J. M. GAMBILL M.D.3

1 Director of Research, Department of Mental Health, Raleigh, North Carolina
2 Clinical Director for Research, Broughton Hospital, Research Psychiatrist, Department of Mental Health, Raleigh, North Carolina
3 Director of Female Geriatric Service, Broughton Hospital, Morganton, North Carolina

This study reports the results of a trial of amitriptyline and imipramine in depressed female patients. A specific finding was that both drugs were effective, and equally effective. These findings are compared and contrasted with a previous study by Hordern, Holt, Burt and Gordon (1963). Differences are explained by the criteria of case selection and drug dosage in the two studies. A more fundamental principle is to illustrate the importance of adequate, specific information and methodology in reporting drug treatment studies so that contrasts and comparisons such as these can be made.




This article has been cited by other articles:


Home page
 Arch Gen PsychiatryHome page
J. C. Nelson and M. B. Bowers Jr
Delusional Unipolar Depression: Description and Drug Response
Arch Gen Psychiatry, November 1, 1978; 35(11): 1321 - 1328.
[Abstract] [PDF]

Home page
 Arch Gen PsychiatryHome page
V. E. Ziegler, P. J. Clayton, and J. T. Biggs
A Comparison Study of Amitriptyline and Nortriptyline With Plasma Levels
Arch Gen Psychiatry, May 1, 1977; 34(5): 607 - 612.
[Abstract] [PDF]

Home page
 Arch Gen PsychiatryHome page
R. J. Bielski and R. O. Friedel
Prediction of Tricyclic Antidepressant Response: A Critical Review
Arch Gen Psychiatry, December 1, 1976; 33(12): 1479 - 1489.
[Abstract] [PDF]

Home page
 Arch Gen PsychiatryHome page
J. B. Morris and A. T. Beck
The Efficacy of Antidepressant Drugs: A Review of Research (1958 to 1972)
Arch Gen Psychiatry, May 1, 1974; 30(5): 667 - 674.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1965 The Royal College of Psychiatrists.