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The British Journal of Psychiatry (1965) 111: 176-182. doi: 10.1192/bjp.111.471.176
© 1965 The Royal College of Psychiatrists
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Urinary Metabolites of some Monoamines and Clinical Effects under Reserpine and Chlorpromazine

R. BOZZI M.D.1, A. BRUNO M.D.2, and A. ALLEGRANZA M.D.3

1 Director, Psychiatric Hospital of Milan, via Ippocrate 45, Milano 10/3, Italy
2 Chief of the Department of Pathology, Psychiatric Hospital of Milan, via Ippocrate 45, Milano 10/3, Italy
3 Assistant, Psychiatric Hospital of Milan, via Ippocrate 45, Milano 10/3, Italy

The relationships between the changes in the urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and vanilmandelic acid (VMA) and the side-effects and clinical responses due to reserpine and chlorpromazine therapy were studied in a group of 18 male schizophrenics.




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