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The British Journal of Psychiatry (1965) 111: 521-525. doi: 10.1192/bjp.111.475.521
© 1965 The Royal College of Psychiatrists
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A Sequential Trial of Wy 3498 (Oxazepam)

JOHN LE GASSICKE M.B., M.R.C.P.E., D.P.M.1 and FRANK M. McPHERSON M.A., Dip. C1in.Psychol.2

1 Consultant Psychiatrist, St. George's Hospital, Morpeth, Northumberland
2 Lecturer in Psychology, Department of Psychological Medicine, University of Edinburgh; Professorial Unit, Jordanburn Nerve Hospital, Edinburgh, 10

A sequential trial of Wy 3498 (Oxazepam) a sedative, was carried out on out-patients with marked anxiety. 10 mg. and 15 mg. t.i.d. doses were compared with each other and with a placebo. The results confirm a previous pilot-study suggesting that the drug is useful in the treatment of psychoneurotic anxiety: no difference between the two dose levels was found. The possibility of mild side-effects with the 15 mg. dose suggests that the 10 mg. dose would be more suitable for general use.

Submitted on July 27, 1964






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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1965 The Royal College of Psychiatrists.