The British Journal of Psychiatry (1966) 112: 135-144. doi: 10.1192/bjp.112.483.135
© 1966 The Royal College of Psychiatrists
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Lumbar Air Encephalography in Chronic Schizophrenia: A Controlled Experiment

P. B. STOREY M.B., M.R.C.P., D.P.M.1

1 Senior Lecturer in Psychiatry, St. George's Hospital, London, S.W.1

The literature on the encephalographic demonstration of cerebral atrophy in chronic schizophrenic patients is briefly reviewed. The absence of adequate control series is discussed.

Eighteen patients and eighteen controls were examined by lumbar air encephalography. The controls were films previously described as "normal" following diagnostic L.A.E.G. for various reasons. Two observers examined the films independently using a blind technique. When measuring, their correlation was good; but they differed significantly in their subjective assessments of abnormality. No significant differences were found between patients and controls. No relationship was found within the patient series which linked the size of the ventricles and such factors as: age, duration of the illness, severity of illness, or amount of somatic treatment. Paranoid patients were found to have broader third ventricles than had hebephrenics, but this is dismissed as being probably accidental.

Some suggestions for further research are made.

Submitted on February 8, 1965




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