Meissner Corpuscles in Skin Biopsies of Patients with Presenile Dementia: A Quantitative Study
RICHARD HUNTER M.D., M.R.C.P., D.P.M.1,
ALAN RIDLEY M.D., Ph.D., M.R.C.P.2, and
ANDREW MALLESON M.B., M.R.C.P., D.P.M.3
1 Physician in Psychological Medicine, The National Hospital, Queen Square, W.C.1; Consultant Psychiatrist, Friern and Whittington Hospitals, London
2 M.R.C. Research Group in Applied Neurobiology, Institute of Neurology, Queen Square, W.C.1
3 Senior Registrar, Friern Hospital, London
Meissner corpuscles in biopsied digital skin of 14 patients with various types of presenile dementia were counted. Their number did not differ from that of normal persons of the same age. Our results suggest that in this group of disorders the pathological processes, whatever they may be, which affect the brain do not affect the primary sensory neurone.
Submitted on February 26, 1968
