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The British Journal of Psychiatry (1970) 117: 157-161. doi: 10.1192/bjp.117.537.157
© 1970 The Royal College of Psychiatrists
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The Effect of Cyclandelate on Mental Function in Patients with Arteriosclerotic Brain Disease

E. W. FINE M.B., B.Ch., D.P.M.1, D. LEWIS M.R.C.S., L.R.C.P., D.P.M.2, I. VILLA-LANDA B.A.3, and C. B. BLAKEMORE B.Sc., Dip. Psych.4

1 Senior Registrar, Morgannwg Hospital, Bridgend
2 Consultant Psychiatrist, Whitchurch Hospital, Cardiff
3 Senior Clinical Psychologist, Whitchurch Hospital, Cardiff
4 Principal Psychologist, Cane Hill Hospital, Coulsdon, Surrey

A double-blind crossover trial is described in which the effect of cyclandelate is assessed on 40 patients admitted to a psychiatric hospital who were severely handicapped with symptoms due to arteriosclerotic brain disease. Significant improvement was observed in a number of important mental functions, suggesting that enhancing the cerebral circulation produces a favourable clinical response in this category of patient.

Submitted on May 14, 1969







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Copyright © 1970 The Royal College of Psychiatrists.