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The British Journal of Psychiatry (1970) 117: 261-266. doi: 10.1192/bjp.117.538.261
© 1970 The Royal College of Psychiatrists
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The Clinical Distinction between the Affective Psychoses and Schizophrenia

R. E. KENDELL M.D., M.R.C.P., D.P.M.1 and JANE GOURLAY M.A.2

1 Senior Lecturer, The Institute of Psychiatry, The Maudsley Hospital, London, S.E.5
2 Research Worker, The Institute of Psychiatry, The Maudsley Hospital, London, S.E.5

In an attempt to determine whether schizophrenic and affective illnesses are distinct entities or whether mixed states are really commoner than 'pure' forms of either, a discriminant function analysis was performed on clinical data from 146 schizophrenics and 146 patients with affective psychoses. The results were equivocal. The distribution of the weighted scores of the 292 patients on the disciminant function differed significantly from a normal distribution, but the distribution was trimodal rather than bimodal, and the boundary between schizophrenic and affective patients was at the peak of the distribution. Discrimination between the two groups was, however, better than that obtained in an analogous study of psychotic and neurotic depressions, and it is possible that the inclusion of data covering the outcome of the illness would increase discrimination to the point at which a bimodal distribution would be demonstrable.

Submitted on December 11, 1969




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Copyright © 1970 The Royal College of Psychiatrists.