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Based on a clinical analysis of 11 cases, a syndrome of mutism induced by phenothiazine derivatives, is described. A central feature was impairment of vocalization, the decline of which ranged from loss of phonation to anarthria. Concomitant with these changes was diminution of psychomotor activities eventually leading to akinetic mutism (coma vigil).
Submitted on November 25, 1971
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