The British Journal of Psychiatry 132: 139-144 (1978)
© 1978 The Royal College of Psychiatrists
Hallucinogenic N-methylated indolealkylamines in the cerebrospinal fluid of psychiatric and control populations
L Corbett, ST Christian, RD Morin, F Benington and JR Smythies
The incidence and quantities of dimethyltryptamine and O- methylbufotenine
were studied in the cerebrospinal fluid of patients suffering acute
schizophrenic illnesses and in surgical and neurological control groups.
Some schizophrenic patients have higher levels of both amines than do
controls, though the differences in distribution did not reach statistical
significance in the sample studied. The gas-chromatographic technique used
is sensitive at the low picogram level.