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The British Journal of Psychiatry 133: 211-218 (1978)
© 1978 The Royal College of Psychiatrists

A study of thyroid function in psychiatric in-patients

DG McLarty, WA Ratcliffe, JG Ratcliffe, JG Shimmins and A Goldberg

The prevalence of abnormal serum total thyroxine (T4) and triiodothyronine (T3) concentrations were determined in 1,206 in- patients in two associated psychiatric hospitals. The biochemical pattern of primary hypothyroidism occurred in five females and one male (prevalence 0.5 per cent), but in only one patient was the diagnosis clinically obvious. Eight patients (all female) were clinically hyperthyroid (prevalence 0.7 per cent), of whom six were previously undiagnosed. There was no evidence that phenothiazines or benzodiazepine therapy had any significant effect on thyroid hormone levels. The small differences in thyroid hormone levels between psychiatric diagnostic groups could be explained by differences in age distribution.





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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1978 The Royal College of Psychiatrists.