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The British Journal of Psychiatry 136: 59-72 (1980)
© 1980 The Royal College of Psychiatrists

Patterns of peptides and protein-associated-peptide complexes in psychiatric disorders

OE Trygstad, KL Reichelt, I Foss, PD Edminson, G Saelid, J Bremer, K Hole, H Orbeck, JH Johansen, JB Boler, K Titlestad and PK Opstad

Peptidic neurones may be considered as multisignal intergrators and transducers. When formation or release of peptide outstrips genetically determined breakdown capacity, overflow of peptides to the body fluids and urine may be expected. In this paper, pathological urinary chromatographic patterns of peptides are shown for genetic, functional and mixed disorders. Part symptoms of the disorders may be induced with the biologically isolated and purified peptides as well as with chemically synthesized peptides.


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Copyright © 1980 The Royal College of Psychiatrists.