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The British Journal of Psychiatry 136: 479-485 (1980)
© 1980 The Royal College of Psychiatrists

Lithium treatment in post-psychotic depression

DP van Kammen, PE Alexander and WE Bunney Jr

Six of eleven drug-free schizophrenic patients who were depressed following remission of their illness showed a significant decrease in their depressive symptomatology during a double-blind, placebo substitution lithium trial. Traditional indicators of prognosis did not predict lithium response in this small sample; the schizophrenic patients tolerated the lithium well. Lithium should be studied further in a larger patient sample as an adjunct in the treatment of post- psychotic depression, which frequently is treatment resistant.




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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1980 The Royal College of Psychiatrists.