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The British Journal of Psychiatry 137: 240-244 (1980)
© 1980 The Royal College of Psychiatrists

Sodium valproate in schizophrenia: some biochemical correlates

A Lautin, B Angrist, M Stanley, S Gershon, K Heckl and M Karobath

Sodium valproate given in doses of 750-3000 mg daily to eight schizophrenic patients produced a qualitatively similar increase in symptoms in five. CSF showed no significant change in gamma-amino- butyric acid or methoxy hydroxyphenyl glycol, but homovanillic acid increased non-significantly in five patients.


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L. Citrome, J. Levine, and B. Allingham
Changes in Use of Valproate and Other Mood Stabilizers for Patients With Schizophrenia From 1994 to 1998
Psychiatr Serv, May 1, 2000; 51(5): 634 - 638.
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Copyright © 1980 The Royal College of Psychiatrists.