The British Journal of Psychiatry 137: 332-336 (1980)
© 1980 The Royal College of Psychiatrists
A stepped forty-eighty hour manic-depressive cycle
C Paschalis, A Pavlou and A Papadimitriou
This paper describes a patient with an almost 48-hour manic-depressive
cycle but with a daily shift of the switching time, the latter having
itself a cycle of five days. The mood change always occurred gradually and
during the day, never at night. Between manic and depressive phases there
was a difference in the frequency of the EEG alpha rhythm. The patient
showed a good response to lithium treatment.