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The British Journal of Psychiatry 137: 444-451 (1980)
© 1980 The Royal College of Psychiatrists

Long-term monitoring of tricyclic antidepressant plasma concentrations

H Loo, AK Benyacoub, V Rovei, CA Altamura, M Vadrot and PL Morselli

Plasma levels of antidepressant drugs were measured in 17 depressed patients at roughly monthly intervals over follow-up periods of three to 26 months. Good results in seven were associated with small fluctuations in level from visit to visit, while big fluctuations were associated with poor outcome. Such fluctuations were probably from poor compliance or drug interaction from self-medication. Severe side effects and cardiotoxicity were associated with high levels.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1980 The Royal College of Psychiatrists.