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The British Journal of Psychiatry 137: 518-521 (1980)
© 1980 The Royal College of Psychiatrists

Clinical state, plasma levels of haloperidol and prolactin: a correlation study in chronic schizophrenia

VA Rao, M Bishop and A Coppen

Chronic schizophrenic patients were maintained for six months on a dosage of haloperidol adjusted to give optimum clinical effect. A correlation was found between extrapyramidal symptoms and prolactin levels and also between plasma haloperidol concentration and plasma prolactin levels. Estimation of plasma prolactin would be a reliable measurement of patients' compliance with medication.


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J.S. Bamrah, J. Krska, and S. D. Soni
Relationship between extrapyramidal symptoms and serum anticholinergic levels in treated chronic schizophrenics
J Psychopharmacol, January 1, 1988; 2(1): 39 - 46.
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 J PsychopharmacolHome page
F.W.A. Browne, S.J. Cooper, R. Wilson, and D.J. King
Serum haloperidol levels and clinical response in chronic, treatment-resistant schizophrenic patients
J Psychopharmacol, January 1, 1988; 2(2): 94 - 103.
[Abstract] [PDF]


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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1980 The Royal College of Psychiatrists.