The British Journal of Psychiatry 138: 361-372 (1981)
© 1981 The Royal College of Psychiatrists
Identification of the endogenous depressive syndrome based on the symptoms and the characteristics of the course
P Matussek, M Soldner and D Nagel
Using a sample of 198 depressed patients (145 female, 53 male)
retrospective histories of the illnesses were collected during a
depression-free interval, based on a catalogue containing 38 symptom items
and the course of the depression (including the interval personality). A
cluster analysis on persons and items filtered out an endogenous depressive
item profile, corresponding with the clinical syndrome of patients
diagnosed as endogenous depressives in the clinics, although determined
without reference to the clinical diagnoses. Our study supports many
results from earlier multivariate statistical studies. We consider our data
to be an essential contribution towards the establishment of a multiaxial
clinical picture.