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The British Journal of Psychiatry 138: 470-473 (1981)
© 1981 The Royal College of Psychiatrists

Amphetamine-induced dysphoria in postmenopausal women

U Halbreich, G Asnis, D Ross and J Endicott

Dextroamphetamine (0.15 mg/kg) intravenously administered to a group of normal postmenopausal women induced a dysphoric reaction with drowsiness, annoyance, sadness and anger. Young normal men, receiving the same dosage, responded with elation of mood and alertness. It is suggested that age and hypoestrogenism may alter the behavioural response to amphetamine.


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Copyright © 1981 The Royal College of Psychiatrists.