The British Journal of Psychiatry 138: 501-503 (1981)
© 1981 The Royal College of Psychiatrists
A study of naloxone with schizophrenic and manic patients
BB Sethi and R Prakash
Eleven schizophrenic and three manic patients were randomly administered
0.3 mg/Kg b.wt. of naloxone or placebo in a drug-free state using a double
blind procedure. BPRS and CGI were employed for making periodic assessment
of mental status; the MRS was additionally used for manic patients. The
authors discuss their findings, which are essentially negative.