The British Journal of Psychiatry 139: 313-318 (1981)
© 1981 The Royal College of Psychiatrists
Derealization syndrome and the outcome of schizophrenia: a report from the international pilot study of schizophrenia
HG Hwu, CC Chen, MT Tsuang and WS Tseng
Eighty-five schizophrenic patients were found to have worse two-year
follow-up outcome (history of remission, clinical course, improvement in
psychotic symptoms, general treatment result) than 39 non- schizophrenic
psychotic patients. The outcome of 36 schizophrenic patients with
derealization at initial evaluation, especially when nine hebephrenics were
excluded, was better than that of 49 schizophrenic patients without
derealization but similar to that of 39 non- schizophrenic patients. The
hebephrenics with derealization demonstrated similar outcomes to
schizophrenic patients without derealization. In non-schizophrenic
patients, derealization had no prognostic significance.