The British Journal of Psychiatry 140: 44-49 (1982)
© 1982 The Royal College of Psychiatrists
Immunological indices in the cerebrospinal fluid of patients with presenile dementia of the Alzheimer type
C Jonker, P Eikelenboom and P Tavenier
In ten patients with presenile dementia of the Alzheimer type and in a
control group the levels of the different immunoglobulins were determined
in both serum and cerebrospinal fluid (CSF), and gel electrophoretic
techniques used to determine possible oligoclonal bands in the
gamma-globulin region. There is no indication that patients with Alzheimer
disease produce immunoglobulins within the central nervous system.