The British Journal of Psychiatry 140: 607-610 (1982)
© 1982 The Royal College of Psychiatrists
HLA antigens in schizophrenia: no difference between patients with and without evidence of brain atrophy
E Frangos, N Renieri-Livieratou, G Athanassenas, E Stavropoulou-Ghioka and A Kourkoubas
The HLA antigens distribution was studied in 56 chronic schizophrenic
in-patients with or without brain atrophy determined by CAT examination,
and compared with that of 200 controls. There was no difference in the
incidence of HLA-A2 in the whole sample, and an increase in those without
brain atrophy (by comparison with normal controls) failed to reach
statistical significance. A decrease of Bw35 in the whole sample, more
prominent in those without brain atrophy, again failed to be significant
after multiplying the probability by the number of antigens studied.