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The British Journal of Psychiatry 141: 411-419 (1982)
© 1982 The Royal College of Psychiatrists

Psychological effects, compliance, and response to long-term lithium

B Muller-Oerlinghausen

The most relevant psychological and neuropsychophysiological effects induced by lithium in healthy volunteers or in patients during the free interval are changes of vigilance and possible changes in patients' personality. In EEG terms lithium acts as a "chopper" and induces left- hemispheric asymmetry. Interesting concepts for description of personality changes are the typus melancholicus of Tellenbach and the psychoanalytical view of depression. Effects in an individual patient are heterogeneous and cannot be predicted. Primary and secondary psychological effects may influence compliance, and a detailed analysis of compliance seems necessary.




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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1982 The Royal College of Psychiatrists.