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The British Journal of Psychiatry 143: 513-514 (1983)
© 1983 The Royal College of Psychiatrists

Short-course diphenoxylate hydrochloride for treatment of methadone withdrawal symptoms

TJ Ives and CC Stults

The authors conducted a preliminary trial of a 5-day course of diphenoxylate in the treatment of out-patients with methadone withdrawal symptoms. Diphenoxylate provided substantial relief from detoxification symptoms with no drug-associated adverse effects.