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The British Journal of Psychiatry 145: 508-511 (1984)
© 1984 The Royal College of Psychiatrists

The dexamethasone suppression test in psychotic versus non-psychotic endogenous depression

Z Rihmer, M Arato, E Szadoczky, K Revai, E Demeter, S Gyorgy and P Udvarhelyi

The authors investigated the dexamethasone suppression test (DST) in 93 female patients with primary (endogenous) major depression; in 20 female paranoid schizophrenics, and in 17 healthy females. Depressed patients had a significantly higher rate of abnormal DST response and significantly higher post-dexamethasone serum cortisol levels than schizophrenics and normal controls. The unipolar and bipolar depressives showed a similar profile of DST abnormalities. Depressed patients with psychotic features had a significantly higher rate of positive DST results than non-psychotic patients.


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 Arch Gen PsychiatryHome page
J. A. Posener, C. DeBattista, G. H. Williams, H. C. Kraemer, B. M. Kalehzan, and A. F. Schatzberg
24-Hour Monitoring of Cortisol and Corticotropin Secretion in Psychotic and Nonpsychotic Major Depression
Arch Gen Psychiatry, August 1, 2000; 57(8): 755 - 760.
[Abstract] [Full Text] [PDF]

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 Am. J. PsychiatryHome page
J. C. Nelson and J. M. Davis
DST Studies in Psychotic Depression: A Meta-Analysis
Am J Psychiatry, November 1, 1997; 154(11): 1497 - 1503.
[Abstract] [Full Text]


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Copyright © 1984 The Royal College of Psychiatrists.