The British Journal of Psychiatry 145: 652-656 (1984)
© 1984 The Royal College of Psychiatrists
On the value of P300 event-related potentials in the differential diagnosis of dementia
JP Slaets and C Fortgens
The possible value of event-related potentials (ERPs) in the differential
diagnosis of dementia was investigated in a group of 42 demented elderly
patients, 29 non-demented elderly patients, and 10 healthy young controls.
The auditory evoked potentials were elicited by using target and non-target
auditory stimuli. There was no significant difference in N100 and P200
latency between these groups. Our results indicate an age-related increase
of P300 latency of 0.3 msec/year in the non-demented subjects. There was no
significant difference in P300 latency between demented and non-demented
patients, and the latencies vary widely within the groups of elderly
patients.