The British Journal of Psychiatry 148: 597-599 (1986)
© 1986 The Royal College of Psychiatrists
Does viloxazine really improve sex drive? A double-blind controlled study
D De Leo and G Magni
The action of viloxazine on libido and sex drive was evaluated with a
randomised controlled double-blind trial against placebo on a population of
26 male out-patients affected by primary depression (DSM III).
Modifications in the sexual sphere were assessed by the ad hoc inclusion of
a series of items in the Zung Self-Rating Depression Scale. Thus modified,
the scale was administered at the beginning and the end of a four-week
trial period. Viloxazine proved to have a considerable disinhibiting
effect, whose principal expression level was a return to pre-depression
levels of frequency in sexual relations.