The British Journal of Psychiatry 148: 718-721 (1986)
© 1986 The Royal College of Psychiatrists
Clovoxamine and doxepin in major depressive disorder: a double-blind controlled trial
GJ Lodge and HL Freeman
Clovoxamine, an inhibitor of neuronal uptake of both serotin and
noradrenaline, was compared with doxepin in depressed patients over four
weeks. Antidepressant efficacy was comparable for both drugs, but
clovoxamine might have a special degree of efficacy for patients with more
severe depressive illnesses.