The British Journal of Psychiatry 148: 736-738 (1986)
© 1986 The Royal College of Psychiatrists
Lithium augmentation in the treatment of delusional depression
M Pai, AC White and AG Deane
Five patients suffering with delusional depression, and who were resistant
to tricyclic antidepressants, were successfully treated with lithium
carbonate. Delusional depression does not usually respond to tricyclic
antidepressants, and ECT has been considered the treatment of choice. Such
patients often refuse to acknowledge that they are ill. They, therefore,
understandably often refuse to accept ECT. In order to treat, the Mental
Health Act 1983 must be invoked. Treatment with lithium carbonate is more
acceptable to most patients, and in the cases described, patients agreed to
take this drug whereas they had refused to accept ECT.