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The British Journal of Psychiatry 149: 235-238 (1986)
© 1986 The Royal College of Psychiatrists
GT Phillips, M Gossop and B Bradley
Psychological and drug-related variables and their effect on the severity of withdrawal symptoms were examined in a group of addicts being withdrawn from opiates on an in-patient drug dependence unit. Two psychological factors--neuroticism and the degree of distress expected by the patient--were related to subsequent severity of symptoms. Both are anxiety-related, and may serve to amplify withdrawal symptoms. Surprisingly, drug dose was unrelated to symptom severity.
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