The British Journal of Psychiatry 150: 43-48 (1987)
© 1987 The Royal College of Psychiatrists
Prediction of outcome in depressive illness by the Newcastle Diagnosis Scale. Its relationship with the unipolar/bipolar and DSM-III systems
MW Carney, EH Reynolds and BF Sheffield
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Harrow, Middlesex, UK.
The Newcastle scores of a group of 64 and subsample of 52 severely
depressed inpatients were not normally distributed. Evidence for
discontinuity in these distributions was adduced from the contrast in
outcome between the endogenous and neurotic patients thus defined, the
endogenous consistently doing better than the neurotic group. The
unipolar/bipolar system failed to predict different results for endogenous
and neurotic patients unless unipolar was subdivided into endogenous and
neurotic subgroups. The DSM-III criteria for major depression and
melancholia failed to identify subgroups of differing prognoses.