| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Psychiatric Bulletin | Advances in Psychiatric Treatment | All RCPsych Journals |
|
|
|
||||||||||
|
||||||||||||
The British Journal of Psychiatry 151: 831-833 (1987)
© 1987 The Royal College of Psychiatrists
GR Gaffney, S Kuperman, LY Tsai, S Minchin and KM Hassanein
College of Health Sciences, University of Kansas, Kansas City 66103.
Since recent reports suggest structural brain abnormalities in autistic patients, we analysed magnetic resonance imaging (MRI) scans of autistic children. Planimetric measurements were done on midsagittal MRI scans, produced with a 0.5 T superconducting magnet. Scans of 13 'high-level' autistic subjects were compared with 35 control MRI scans, read as anatomically normal by a neuroradiologist. Corpus callosal, fourth ventricular, cerebellar, cerebral, and cranial areas were measured. The fourth ventricle was found to be significantly larger in the autistic group. No other areas in the midsagittal scans differed statistically between groups. Results suggest that structures defining the fourth ventricle are anatomically altered in autistic patients.
This article has been cited by other articles:
|
|
 |
|
  G. M. McAlonan, E. Daly, V. Kumari, H. D. Critchley, T. v. Amelsvoort, J. Suckling, A. Simmons, T. Sigmundsson, K. Greenwood, A. Russell, et al. Brain anatomy and sensorimotor gating in Asperger's syndrome Brain, July 1, 2002; 125(7): 1594 - 1606. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Elia, R. Ferri, S. A. Musumeci, S. Panerai, M. Bottitta, and C. Scuderi Clinical Correlates of Brain Morphometric Features of Subjects With Low-Functioning Autistic Disorder J Child Neurol, August 1, 2000; 15(8): 504 - 508. [Abstract] [PDF]
|
|
|
|
 |
|
 F. Manes, J. Piven, D. Vrancic, V. Nanclares, C. Plebst, and S. E. Starkstein An MRI Study of the Corpus Callosum and Cerebellum in Mentally Retarded Autistic Individuals J Neuropsychiatry Clin Neurosci, November 1, 1999; 11(4): 470 - 474. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Egaas, E. Courchesne, and O. Saitoh Reduced Size of Corpus Callosum in Autism Arch Neurol, August 1, 1995; 52(8): 794 - 801. [Abstract] [PDF]
|
|
|
|
|
|
T. Hashimoto, M. Tayama, M. Miyazaki, K. Murakawa, and Y. Kuroda Brainstem and Cerebellar Vermis Involvement in Autistic Children J Child Neurol, April 1, 1993; 8(2): 149 - 153. [Abstract] [PDF]
|
|
|
|
|
|
M. Hsu, R. Yeung-Courchesne, E. Courchesne, and G. A. Press Absence of Magnetic Resonance Imaging Evidence of Pontine Abnormality in Infantile Autism Arch Neurol, November 1, 1991; 48(11): 1160 - 1163. [Abstract] [PDF]
|
|
|
|
 |
|
 G. W. Hynd, M. Semrud-Clikeman, A. R. Lorys, E. S. Novey, D. Eliopulos, and H. Lyytinen Corpus Callosum Morphology in Attention Deficit-Hyperactivity Disorder: Morphometric Analysis of MRI J Learn Disabil, March 1, 1991; 24(3): 141 - 146. [Abstract] [PDF]
|
|
|
|
|
|
J. W. Murakami, E. Courchesne, G. A. Press, R. Yeung-Courchesne, and J. R. Hesselink Reduced Cerebellar Hemisphere Size and Its Relationship to Vermal Hypoplasia in Autism Arch Neurol, June 1, 1989; 46(6): 689 - 694. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Psychiatric Bulletin | Advances in Psychiatric Treatment | All RCPsych Journals |
