The British Journal of Psychiatry 152: 372-376 (1988)
© 1988 The Royal College of Psychiatrists
A study of sulphatoxymelatonin excretion and gonadotrophin status during weight gain in anorexia nervosa
J Bearn, J Treasure, M Murphy, C Franey, J Arendt, M Wheeler and SA Checkley
Institute of Psychiatry, London.
To clarify a controversy as to whether melatonin secretion is related to
body weight, urinary sulphatoxymelatonin (aMT6s) excretion was estimated in
10 patients with anorexia nervosa before and after weight gain, and
compared with 10 age-matched controls. There was no change in aMT6s
excretion after weight gain, and no significant difference between the
patients and control groups at either point. Significant increases in
plasma LH, FSH, and estradiol were detected after weight gain in anorexic
patients, independent of aMT6s excretion.