The British Journal of Psychiatry 152: 535-538 (1988)
© 1988 The Royal College of Psychiatrists
Supervising lithium. A comparison of a lithium clinic, psychiatric out- patient clinics, and general practice
G Masterton, M Warner and B Roxburgh
Yeovil District Hospital.
Supervision of lithium treatment among three groups of patients treated in
different settings - at a lithium clinic, as hospital out-patients, and by
a GP - was studied. The lithium clinic maintained lower levels and checked
these more frequently. Elevated lithium levels were most frequent in the
GP-supervised group, which also included the 13 patients with the most
impaired glomerular filtration. In hospital settings GFR-impaired patients
received a lower daily dose of lithium; in general practice, affected
patients had a higher mean serum lithium level and were more frequently
prescribed lithium once daily. We conclude that patients with glomerular
impairment who require lithium should be supervised by a specialist, or at
least prescribed lithium in divided daily doses.