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The British Journal of Psychiatry 153: 102-104 (1988)
© 1988 The Royal College of Psychiatrists

Hypothyroidism in Down's syndrome

C Mani
Northgate Hospital, Northumberland, Scotland.

Fifty-five adult Down's syndrome subjects resident at Northgate Hospital were screened for the presence of thyroid dysfunction. Approximately 50% of the subjects had clinical features suggestive of hypothyroidism, sufficient to require thyroid-function tests. Twenty- two per cent of the total suffered from some degree of hypothyroidism, and 16% had positive antibodies to thyroid tissue.


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K. N. Carroll, P. G. Arbogast, J. A. Dudley, and W. O. Cooper
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S E Noble, K Leyland, C A Findlay, C E Clark, J Redfern, J M Mackenzie, R W A Girdwood, and M D C Donaldson
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Copyright © 1988 The Royal College of Psychiatrists.