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The British Journal of Psychiatry 153: 187-190 (1988)
© 1988 The Royal College of Psychiatrists

Dementia praecox revisited. Age disorientation, mental status, and ventricular enlargement

TE Goldberg, JE Kleinman, DG Daniel, MS Myslobodsky, JD Ragland and DR Weinberger
Clinical Brain Disorders Branch, Neurosciences Research Center at St Elizabeths, Washington DC 20032.

Thirty-nine patients with DSM-III diagnoses of schizophrenia were examined for age disorientation, an inability to produce one's correct chronological age upon request. Six patients were age-disoriented and demented (as defined by Mini-Mental State evaluation), while two patients had delusions concerning their age, but were not demented. Age- disoriented, demented patients had very large cerebral ventricles and very low Mini-Mental State scores. This group differed on the cognitive and neuroanatomic variables from other demented, but not age- disoriented, patients, as well as from non-demented patients who were age-oriented. The age-disoriented patients appeared to be at an extreme end of the dementia spectrum in schizophrenia.


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 J. Neurol. Neurosurg. PsychiatryHome page
P J de Vries, W G Honer, P M Kemp, and P J McKenna
Dementia as a complication of schizophrenia
J. Neurol. Neurosurg. Psychiatry, May 1, 2001; 70(5): 588 - 596.
[Abstract] [Full Text] [PDF]


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Copyright © 1988 The Royal College of Psychiatrists.