BJP College Seminars Series
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lichtenberg, P.
Right arrow Articles by Lerer, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lichtenberg, P.
Right arrow Articles by Lerer, B.

The British Journal of Psychiatry 153: 387-389 (1988)
© 1988 The Royal College of Psychiatrists

Post-partum psychosis in adult GM2 gangliosidosis. A case report

P Lichtenberg, R Navon, E Wertman, H Dasberg and B Lerer
Department of Psychiatry, Jerusalem Mental Health Center.

Adult hexosaminidase A deficiency is a form of GM2 gangliosidosis with autosomal recessive inheritance. Only 35 cases (mostly among Ashkenazic Jews) have been reported worldwide. Symptoms include, in a third of the cases, psychosis. A 27-year-old sufferer with no prior psychiatric history, developed a post-partum psychosis, with affective and hebephrenic components, 3 days following her first delivery. She responded to lithium within 10 days of initiating treatment; the full episode lasted 1 month. We conclude that lithium is the preferred treatment for psychosis in such adult patients, especially in light of possible long-term neurological deterioration caused by phenothiazines. Ashkenazic Jews with atypical neurological syndromes presenting with psychosis should be tested for hexosaminidase A deficiency.


This article has been cited by other articles:


Home page
 PediatricsHome page
G. H. B. Maegawa, T. Stockley, M. Tropak, B. Banwell, S. Blaser, F. Kok, R. Giugliani, D. Mahuran, and J. T.R. Clarke
The Natural History of Juvenile or Subacute GM2 Gangliosidosis: 21 New Cases and Literature Review of 134 Previously Reported
Pediatrics, November 1, 2006; 118(5): e1550 - e1562.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
L. C. Frey, S. P. Ringel, and C. M. Filley
The Natural History of Cognitive Dysfunction in Late-Onset GM2 Gangliosidosis
Arch Neurol, June 1, 2005; 62(6): 989 - 994.
[Abstract] [Full Text] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
G. M. MacQueen, P. I. Rosebush, and M. F. Mazurek
Neuropsychiatric Aspects of the Adult Variant of Tay-Sachs Disease
J Neuropsychiatry Clin Neurosci, February 1, 1998; 10(1): 10 - 19.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1988 The Royal College of Psychiatrists.