The British Journal of Psychiatry 154: 705-708 (1989)
© 1989 The Royal College of Psychiatrists
The occurrence of depression following mania. A method of predicting vulnerable cases
CP Lucas, JC Rigby and SB Lucas
High Royds Hospital, Menston, Ilkley.
In a retrospective analysis of 100 cases of mania (1981-1985), the
incidence of subsequent depression was found to be 30%. Its occurrence was
significantly associated with three factors: cyclothymic pre-morbid
personality, family history of affective disorder, and past history of
depression. By discriminant analysis, outcome could be predicted
successfully in 81% of cases.