| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Psychiatric Bulletin | Advances in Psychiatric Treatment | All RCPsych Journals |
|
|
|
||||||||||
|
||||||||||||
The British Journal of Psychiatry 158: 158-164 (1991)
© 1991 The Royal College of Psychiatrists
AH Young, DH Blackwood, H Roxborough, JK McQueen, MJ Martin and D Kean
University Department of Psychiatry, Royal Edinburgh Hospital.
Thirty-one patients with schizophrenia and 33 normal control subjects underwent MRI. The BPRS was used to rate clinical symptoms and the NART to estimate pre-morbid IQ. All were right handed. The temporal lobe was significantly smaller on the left than the right in both the control and schizophrenic groups. The amygdala was smaller on the left than the right in controls but not in schizophrenics. The parahippocampal gyrus was smaller on the left side in the schizophrenic group but not in controls. In the schizophrenic group, ventricular enlargement and cerebral atrophy were significantly related to severity of symptoms. Patients with marked negative symptoms had a bilateral reduction in the size of the head of caudate and the two measures were significantly correlated. Patients with marked positive symptoms had larger VBRs and again the clinical and morphometric changes were significantly correlated. There were no morphometric differences between patients with short duration (two years or less) and chronic symptoms.
This article has been cited by other articles:
|
|
 |
|
  K. Sim, I. DeWitt, T. Ditman, M. Zalesak, I. Greenhouse, D. Goff, A. P Weiss, and S. Heckers Hippocampal and Parahippocampal Volumes in Schizophrenia: A Structural MRI Study Schizophr Bull, April 1, 2006; 32(2): 332 - 340. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Kaur, R. B. Sassi, D. Axelson, M. Nicoletti, P. Brambilla, E. S. Monkul, J. P. Hatch, M. S. Keshavan, N. Ryan, B. Birmaher, et al. Cingulate Cortex Anatomical Abnormalities in Children and Adolescents With Bipolar Disorder Am J Psychiatry, September 1, 2005; 162(9): 1637 - 1643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. E. Gur, B. I. Turetsky, P. E. Cowell, C. Finkelman, V. Maany, R. I. Grossman, S. E. Arnold, W. B. Bilker, and R. C. Gur Temporolimbic Volume Reductions in Schizophrenia Arch Gen Psychiatry, August 1, 2000; 57(8): 769 - 775. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Krabbendam, M. M. A. Derix, A. Honig, E. Vuurman, R. Havermans, J. T. Wilmink, and J. Jolles Cognitive Performance in Relation to MRI Temporal Lobe Volume in Schizophrenic Patients and Healthy Control Subjects J Neuropsychiatry Clin Neurosci, May 1, 2000; 12(2): 251 - 256. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Velakoulis, C. Pantelis, P. D. McGorry, P. Dudgeon, W. Brewer, M. Cook, P. Desmond, N. Bridle, P. Tierney, V. Murrie, et al. Hippocampal Volume in First-Episode Psychoses and Chronic Schizophrenia: A High-Resolution Magnetic Resonance Imaging Study Arch Gen Psychiatry, February 1, 1999; 56(2): 133 - 141. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. R. Highley, M. M. Esiri, B. McDonald, M. Cortina-Borja, B. M. Herron, and T. J. Crow The size and fibre composition of the corpus callosum with respect to gender and schizophrenia: a post-mortem study Brain, January 1, 1999; 122(1): 99 - 110. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. S. Keshavan, D. Rosenberg, J. A. Sweeney, and J. W. Pettegrew Decreased Caudate Volume in Neuroleptic-Naive Psychotic Patients Am J Psychiatry, June 1, 1998; 155(6): 774 - 778. [Abstract] [Full Text]
|
|
|
|
|
|
M. D. Nelson, A. J. Saykin, L. A. Flashman, and H. J. Riordan Hippocampal Volume Reduction in Schizophrenia as Assessed by Magnetic Resonance Imaging: A Meta-analytic Study Arch Gen Psychiatry, May 1, 1998; 55(5): 433 - 440. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Psychiatric Bulletin | Advances in Psychiatric Treatment | All RCPsych Journals |
