The British Journal of Psychiatry 158: 416-419 (1991)
© 1991 The Royal College of Psychiatrists
Gilles de la Tourette syndrome in the Middle East. Report of a cohort and a multiply affected large pedigree
MM Robertson and MR Trimble
Institute of Neurology, UCMSM, Middlesex Hospital, London.
In a cohort of five patients from the Middle East with the Gilles de la
Tourette syndrome, family history of a tic disorder or the Gilles de la
Tourette syndrome was positive in three cases. In one of these there was a
multiply affected pedigree spanning six generations. The phenomenology of
the syndrome is the same as that described in Western reports. The familial
pattern of inheritance and cross-cultural similarity emphasise the
biological factors in the aetiology of the syndrome.