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The British Journal of Psychiatry 159: 226-231 (1991)
© 1991 The Royal College of Psychiatrists

Changes in the positive and negative symptoms of schizophrenic in- patients in China

MR Phillips, ZA Zhao, XZ Xiong, XF Cheng, GR Sun and NS Wu
Research Centre of Psychological Medicine, Shashi Psychiatric Hospital, Hubei, People's Republic of China.

Positive and negative symptoms at admission and discharge of 401 unselected schizophrenic patients from four psychiatric hospitals around China were studied. On admission 58% of patients had prominent negative symptoms and the overall severity of negative symptoms was similar to that of positive symptoms; at discharge, negative symptoms were more prevalent and more severe. The severity of negative symptoms was not significantly correlated with duration of illness or with dosage of medication; 48% of first-episode, drug-naive patients had prominent negative symptoms on admission. Negative symptoms responded to standard neuroleptic treatment, but the improvement was less marked than that in positive symptoms (47% v. 80%). The proportion of patients classified as positive type, negative type, and mixed type schizophrenia altered dramatically with treatment. These findings highlight the importance of negative symptoms in the assessment and treatment of both acute and chronic schizophrenia.


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Copyright © 1991 The Royal College of Psychiatrists.