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The British Journal of Psychiatry 159: 262-266 (1991)
© 1991 The Royal College of Psychiatrists

Neuroendocrine challenge studies in puerperal psychoses. Dexamethasone suppression and TRH stimulation

ES Paykel, AM del Campo, W White and R Horton
Department of Psychiatry, University of Cambridge, Addenbrooke's Hospital.

Subjects admitted to hospital with post-partum psychoses were compared with matched normal post-partum controls using two neuroendocrine challenge tests: dexamethasone suppression of cortisol and TRH stimulation of TSH. Post-dexamethasone cortisol levels were significantly elevated. There were less-clear hints of blunting of TSH response. In the small samples there was no obvious association of abnormalities with any particular diagnoses within the range of mania, psychotic depression and schizoaffective disorders.





HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1991 The Royal College of Psychiatrists.