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The British Journal of Psychiatry 159: 433-435 (1991)
© 1991 The Royal College of Psychiatrists

Serotonin reuptake inhibitors, epilepsy and myoclonus

M Deahl and M Trimble
Medical College of St Bartholomew's Hospital, West Smithfield, London.

Specific inhibitors of 5-HT reuptake are reported to have lower proconvulsive activity than other antidepressants. A patient with post- traumatic epilepsy who had remained fit-free for many years until she was given the 5-HT reuptake inhibitor fluvoxamine is reported. Changes in serotonergic function may play a more widespread role in the pathophysiology of seizure disorders than hitherto thought.


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M.A. Serfaty, L.M. Martin, R. Lingham, and I.N. Ferrier
The effect of psychotropic medication on seizure duration during bilateral electroconvulsive therapy: a retrospective study
J Psychopharmacol, January 1, 1996; 10(4): 303 - 308.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1991 The Royal College of Psychiatrists.