The British Journal of Psychiatry 159: 485-494 (1991)
© 1991 The Royal College of Psychiatrists
Schizophrenia, bipolar disorder and depression. A discriminant analysis, using 'lifetime' psychopathology ratings
IF Brockington, A Roper, J Copas, M Buckley, CE Andrade, P Wigg, A Farmer, C Kaufman and R Hawley
Queen Elizabeth Psychiatric Hospital, Birmingham.
Discriminant and canonical variate analyses were performed using 302
patients, on whom ratings of lifetime psychopathology and course of illness
has been made. DSM-III diagnoses were used to form the criterion groups.
Bipolar disorder emerged as a distinct grouping, but there are reasons for
dissatisfaction with its definition. The remaining patients formed a
'schizodepressive continuum', but this also had a tendency to bimodality.
It is possible that the distinction between schizophrenia and depression
was obscured by inadequacies in the data and the inclusion of excessive
numbers of patients with schizoaffective depression in this study.